Scientific References for Microbiome Analysis Kit
Anaya-Loyola MA, Enciso-Moreno JA, Lopez-Ramos JE, Garcia-Marin G, Orozco Alvarez MY, Vega-Garcai AM, Mosqueda J, Garcia-Gutierrez DG, Keller D, Perez-Ramirez IF. Bacillus coagulans GBI-30, 6086 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican scholar-aged children by modulating immune-related proteins. (2019)
Bach Knudsen, Knud Erik et al. “Impact of Diet-Modulated Butyrate Production on Intestinal Barrier Function and Inflammation.” Nutrients vol. 10,10 1499.
Benyacoub. J., Czarnecki-Maulden, G. L., Cavadini, C., Sauthier, T., Anderson, R. E., Schiffrin, E. J., & von der Weid, T. (2003). Supplementation of food with Enterococcus faecium (SF68) stimulates immune functions in young dogs. Journal of Nutrition, 133(4), 1158–1162.
Buddington, R. K., & Sunvold, G. D. (1998). Fermentable fiber and the gastrointestinal tract ecosystem. Recent Advances in Canine and Feline Nutrition: 1998 Iams Nutrition Symposium Proceedings, pp. 449–461.
Bybee, S. N., Scorza, A. V., & Lappin, M. R. (2011). Effect of the probiotic Enterococcus faecium SF68 on presence of diarrhea in cats and dogs housed in an animal shelter. Journal of Veterinary Internal Medicine, 25(4), 856–60. doi: 10.1111/j.1939-1676.2011.0738.x
Coelho LP, Kultima JR, Costea PI, et al. Similarity of the dog and human gut microbiomes in gene content and response to diet. Microbiome. 2018 Apr;6(1):72. DOI: 10.1186/s40168-018-0450-3.
Cupp, Carolyn Jean et al. Effect of Nutritional Interventions on Longevity of Senior Cats. Intern J Appl Res Vet Med • Vol. 5, 3, (2007); 133-49.
Cupp, C. J., Kerr, W. W., Jean-Phillipe, C., Patil, A. R., & Perez-Camargo, G. (2008). The role of nutritional interventions in the longevity and maintenance of long-term health in aging cats. International Journal of Applied Research in Veterinary Medicine, 6, 69–81.
Czarnecki-Maulden, G,L. “Fecal Microbiota Changes in Aging Dogs and Cats – Implications for Health and Longevity” Companion animal nutrition summit, May 3-5, 2018 | Charleston, South Carolina
Czarnecki-Maulden, G. L. (2001). Microflora and fiber in the GI tract: Helping the good guys. Veterinary Forum, 18(9), 43–45.
Czarnecki-Maulden, G. (2000). The use of prebiotics in prepared pet food. Veterinary International, 2(1), 19–23.
G Czarnecki-Maulden 2006. Enterococcus faecium SF68 as a Probiotic for Dogs and Cats. Compendium: Continuing Education for Veterinarians 31(3):31
Czarnecki-Maulden G 2008. Effect of dietary modulation of intestinal microbiota on reproduction and early growth Theriogenology 70(3):286-90
Czarnecki-Maulden, G, Binder, S & Saylock M, 2002. Chicory root, a source of soluble fiber, increases apparent calcium digestibility in dogs. FASEB J 16 (4), A654
G.L. Czarnecki-Maulden, A.R. Patil The effect of trial length on canine fecal microflora response to chicory ingestion Joint Nutrition Sympoium, Antwerp, Belgium. J Anim Physiol Anim Nutr (Berl) 2004 Apr;88(3-4)
G Czarnecki-Maulden, AR Patil 2004. Effect of chicory on fecal quality in dogs and cats. Compendium on continuing education for the practicing veterinarian
Czarnecki-Maulden, G. L., & Russell, T. J. (2000a). Effect of chicory on fecal microflora in dogs fed soy-containing or soy-free diets. Federation of American Societies for Experimental Biology Journal, 14(4), A488.
Czarnecki-Maulden, G. L., & Russell, T. J. (2000b). Effect of diet type on fecal microflora in dogs. Federation of American Societies for Experimental Biology Journal, 14(4), A488.
Davis CD. The Gut Microbiome and Its Role in Obesity. Nutr Today. 2016 Jul-Aug;51(4):167-174
Dolin BJ. Effects of A Proprietary Bacillus coagulans Preparation on Symptoms of Diarrhea–Predominant Irritable Bowel Syndrome Methods Find Exp Clin Pharmacol 2009;31:655-9.
Dudek-Wicher, Ruth K et al. “The influence of antibiotics and dietary components on gut microbiota.” Przeglad gastroenterologiczny vol. 13,2 (2018): 85-92.
Fenimore, A., Martin, L., & Lappin, M. R. (2017). Evaluation of metronidazole with and without Enterococcus faecium SF68 in shelter dogs with diarrhea. Topics in Companion AnimalMedicine, 32(3), 100–103. doi: 10.1053 j.tcam.2017.11.001
Gagliardi, Antonella et al. “Rebuilding the Gut Microbiota Ecosystem.” International journal of environmental research and public health vol. 15,8 1679. 7
Garidou L, Pomié C, Klopp P, Waget A, Charpentier J, Aloulou M, Giry A, Serino M, Stenman L, Lahtinen S, Dray C, Iacovoni JS, Courtney M, Collet X, Amar J, Servant F, Lelouvier B, Valet P, Eberl G, Fazilleau N, Douin-Echinard V, Heymes C, Burcelin R. 2015. The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease. Cell Metab. Jul 7;22(1):100-12.
Gepner Y, Hoffman JR, Shemesh E, et al. The Combined Effect of Bacillus Coagulans GBI-30, 6086 and HMB Supplementation on Muscle Integrity and Cytokine Response during Intense Military Training. J Appl Physiol 2017:jap 01116 2016.
Guard, B. C., Mila, H., Steiner, J. M., Mariani, C., Suchodolski, J. S., & Chastant-Maillard, S. (2017). Characterization of the fecal microbiome during neonatal and early pediatric development in puppies. PLoS ONE, 12(4), e0175718. http://doi.org/10.1371/journal.pone.0175718
Hesta, M., Janssens, G. P., Debraekeleer, J., & De Wilde, R. (2001). The effect of oligofructose and inulin on faecal characteristics and nutrient digestibility in healthy cats. Journal of Animal Physiology and Animal Nutrition (Berl), 85, 135–141.
Hun L. Bacillus coagulans Significantly Improved Abdominal Pain and Bloating in Patients With IBS Postgrad Med 2009;121:119-24.
Jäger R, Shields KA, Lowery RP, et al. Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery PeerJ 2016;4:e2276
Jenkins, Cyril W. et al., Inulin, Oligofructose and Intestinal Function, The Journal of Nutrition, vol 129, 7 (1999): 1431S-33S
Kalman DS, Schwartz HI, Alvarez P, Feldman S, Pezzullo JC, Krieger DR. A Prospective, Randomized, Double-blind, Placebo-controlled Parallel-group Dual Site Trial to Evaluate the Effects of a Bacillus coagulans–based Product on Functional Intestinal Gas Symptoms BMC gastroenterology 2009;9:85.
Keller D, Van Dinter R, Cash H, Farmer S, Venema K Bacillus coagulans GBI-30, 6086 increases plant protein digestion in a dynamic, computer-controlled in vitro model of the small intestine Benef Microbes 2017:1-6
Kimmel M, Keller D, Farmer S, Warrino DE. A Controlled Clinical Trial to Evaluate the Effect of GanedenBC30 on Immunological Markers Methods Find Exp Clin Pharmacol 2010;32:129-32.
Knudsen, K., Serena, A., Canibe, N., & Juntunen, K. (2003). New insights into butyrate metabolism. Proceedings of the Nutrition Society, 62, 81–86.
Langille, Morgan G I et al. “Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences.” Nature biotechnology vol. 31,9 (2013): 814-21.
Lappin, M. R., Veir, J. K., Satyaraj, E., & Czarnecki-Maulden, G. L. (2009). Pilot study to evaluate the effect of oral supplementation of Enterococcus faecium SF68 on cats with latent feline herpesvirus 1. Journal of Feline Medicine and Surgery, 11:650–654.
Li, Q, Lauber,CL, Czarnecki-Maulden, G, Pan, Y, Hannah S Effects of the Dietary Protein and Carbohydrate Ratio on Gut Microbiomes in Dogs of Different Body Conditions mBio Jan 2017, 8 (1) e01703-16; DOI: 10.1128/mBio.01703-16
Maathuis AJ, Keller D, Farmer S, Gepner Y, Hoffman JR, Shemesh E, et al. Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine. Benef Microbes 2010;1:31-6.
Nyangale, E, P. et al. “Bacillus coagulans GBI-30, 6086 Modulates Faecalibacterium prausnitzii in Older Men and Women”, The Journal of Nutrition, Vol 145, 7 (2015); (1446–1452)
Patil, A. R., Czarnecki-Maulden, G., & Dowling, K. E. (2000). Effect of advances in age on fecal microflora of cats. Federation of American Societies for Experimental Biology Journal, 14(4), A488.
Patil, A. R., Carrion, P. A., & Holmes, A. K. (2001). Effect of chicory supplementation on fecal microflora of cats. Federation of American Societies for Experimental Biology Journal, 15(4), A288.
Pinna, C., & Biagi, G. (2014). The utilization of prebiotics and synbiotics in dogs. Italian Journal of Animal Science, 13, 169–178.
Ramadan Z, Xu H, Laflamme D, Czarnecki-Maulden G, Li QJ, Labuda J, Bourqui B. 2014. Fecal microbiota of cats with naturally occurring chronic diarrhea assessed using 16S rRNA gene 454-pyrosequencing before and after dietary treatment Journal of Veterinary Internal Medicine 8(1):59-65
Rivière, Audrey et al. “Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut.” Frontiers in microbiology vol. 7 979.
Roberfroid, M. (2007). Prebiotics: The concept revisited. Journal of Nutrition, 173(3) Suppl. 2, 830S–837S.
Rowland, Ian et al. “Gut microbiota functions: metabolism of nutrients and other food components.” European journal of nutrition vol. 57,1 (2018): 1-24.
Rowland, I, J. et al. “Gut microbiota functions: metabolism of nutrients and other food components.” Eur J Nutr, vol. 57: 1. (2018) ; 1445-8
Scott KP et al. “Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro”, FEMS Microbiology Ecology, Vol 87, 1, (2014): 30–40
Simpson, K. W., Rishniw, M., Bellosa, M., Liotta, J., Lucio, A., Baumgart, M., & Bowman, D. (2009). Influence of Enterococcus faecium SF68 probiotic on giardiasis in dogs. Journal of Veterinary Internal Medicine, 23(3):476–481. doi: 10.1111/j.1939–1676.2009.0283.x
Stecker et al. Bacillus coagulans GBI-30, 6086 improves amino acid absorption from milk protein”, Nutrition & Metabolism, 17:93, 23 October 2020
Stenman LK, Lehtinen MJ, Meland N, Christensen JE, Yeung N, Saarinen MT, Courtney M, Burcelin R, Lähdeaho ML, Linros J, Apter D, Scheinin M, Kloster Smerud H, Rissanen A, Lahtinen S. 2016. Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults-Randomized Controlled Trial. EBioMedicine. 2016 Oct 26.
Torres-Henderson, C., Summers, S., Suchodolski, J., & Lappin, M. R. (2017). Effect of Enterococcus faecium strain SF68 on gastrointestinal signs and fecal microbiome in cats administered amoxicillin-clavulanate. Topics in Companion Animal Medicine, 32(3), 104–108. doi: 10.1053/j.tcam.2017.11.002
Valcheva, R., & Dieleman, L. A. (2016). Prebiotics: Definition and protective mechanisms. Best Practice & Research Clinical Gastroenterology, 30, 27–37.
Valdes Ana M, Walter Jens, Segal Eran, Spector Tim D. Role of the gut microbiota in nutrition and health BMJ 2018; 361 :k2179
Veir, J. K., Knorr, R., Cavadini, C., Sherrill, S. J., Benyacoub, J., Satyaraj, E., & Lappin, M. R. (2007). Effect of supplementation with Enterococcus faecium (SF68) on immune functions in cats. Veterinary Therapeutics, 8(4), 229–238.
Waldron, M., Kerr, W., Czarnecki-Maulden, G. L., & Davis, J. (2012). Supplementation with Enterococcus faecium SF68 Reduces Flatulence in Dogs. Presented at the International Scientific Congress of the European Society of Veterinary and Comparative Nutrition, Bydgoszcz, Poland
Williams D, Manuzon M, Ramadan Z, Czarnecki-Maulden GL 2015 Serum cobalamin concentration in geriatric cats and response to oral cobalamin supplementation is associated with differences in the composition of the fecal microbiome Journal of Veterinary Internal Medicine 30 (1), 359
Williams D, Manuzon M, Ramadan Z, Czarnecki-Maulden GL 2016. Cobalamin and the Intestinal Microbiome in Geriatric Cats Gutski Comparative Gastroenterology Society
Younes, H., Garleb, K., Behr, S., Rémésy, C., & Demigné, C. (1995). Fermentable fibers or oligosaccharides reduce urinary nitrogen excretion by increasing urea disposal in the rat cecum. Journal of Nutrition, 125, 1010–1016
Young, W., Moon, C. D., Thomas, D. G., Cave, N. J., & Bermingham, E. N. (2016). Pre- and post-weaning diet alters the faecal metagenome in the cat with differences vitamin and carbohydrate metabolism gene abundances. Scientific Reports, 6, 34668. http://doi.org/10.1038/srep34668
For summaries, see:
https://www.purinainstitute.com/science-of-nutrition/promoting-gastrointestinal-health/prebioticshttps://www.purinainstitute.com/science-of-nutrition/promoting-gastrointestinal-health/probiotic
https://www.purinainstitute.com/can-summit/can-2018-gerontology
https://www.purinainstitute.com/science-of-nutrition/extending-healthy-life/longevity-study-in-cats
https://www.purinainstitute.com/can-summit/can-2018/emerging-evidence-in-nutrient-sensitive-conditions-of-aging-pets/gi-microflora-changes-in-aging-dogs-and-cats
https://www.uspharmacist.com/article/inulin-studies-in-humans-overview-of-health-benefits